1835759-68-6

1835759-68-6 structure
1835759-68-6 structure
  • Name: 1,1,1-Trifluoroethyl-PEG2-azide
  • Chemical Name: 1,1,1-Trifluoroethyl-PEG2-azide
  • CAS Number: 1835759-68-6
  • Molecular Formula: C6H10F3N3O2
  • Molecular Weight: 213.16
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:46:29
  • Modify Date: 2024-01-10 11:56:19
  • 1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,1,1-Trifluoroethyl-PEG2-azide
Description 1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H10F3N3O2
Molecular Weight 213.16