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1835759-73-3

1835759-73-3 structure
1835759-73-3 structure
  • Name: 1,1,1-Trifluoroethyl-PEG3-Propargyl
  • Chemical Name: 1,1,1-Trifluoroethyl-PEG2-propargyl
  • CAS Number: 1835759-73-3
  • Molecular Formula: C9H13F3O3
  • Molecular Weight: 226.19
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:38:41
  • Modify Date: 2024-01-10 06:14:07
  • 1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,1,1-Trifluoroethyl-PEG2-propargyl
Synonyms MFCD29052201
Description 1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C9H13F3O3
Molecular Weight 226.19