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1872433-72-1

1872433-72-1 structure
1872433-72-1 structure
  • Name: 1,1,1-Trifluoroethyl-PEG4-amine
  • Chemical Name: 1,1,1-Trifluoroethyl-PEG4-amine
  • CAS Number: 1872433-72-1
  • Molecular Formula: C10H20F3NO4
  • Molecular Weight: 275.27
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:47:21
  • Modify Date: 2024-01-14 19:52:58
  • 111-Trifluoroethyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,1,1-Trifluoroethyl-PEG4-amine
Synonyms MFCD29079382
Description 111-Trifluoroethyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H20F3NO4
Molecular Weight 275.27