1895922-78-7

1895922-78-7 structure
1895922-78-7 structure
  • Name: 1,1,1-Trifluoroethyl-PEG4-aminooxy
  • Chemical Name: 1,1,1-Trifluoroethyl-PEG4-aminooxy
  • CAS Number: 1895922-78-7
  • Molecular Formula: C10H20F3NO5
  • Molecular Weight: 291.26
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-05 10:54:37
  • Modify Date: 2024-01-10 20:58:32
  • 1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,1,1-Trifluoroethyl-PEG4-aminooxy
Synonyms MFCD29764348
Description 1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H20F3NO5
Molecular Weight 291.26