1817735-37-7

1817735-37-7 structure
1817735-37-7 structure
  • Name: 1,1,1-Trifluoroethyl-PEG5-Propargyl
  • Chemical Name: 1,1,1-Trifluoroethyl-PEG4-propargyl
  • CAS Number: 1817735-37-7
  • Molecular Formula: C13H21F3O5
  • Molecular Weight: 314.30
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:27:52
  • Modify Date: 2024-08-14 10:03:32
  • 1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,1,1-Trifluoroethyl-PEG4-propargyl
Synonyms MFCD29042360
Description 1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H21F3O5
Molecular Weight 314.30