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1310686-23-7

1310686-23-7 structure
1310686-23-7 structure
  • Name: 1-isothiocyanato-PEG3-Azide
  • Chemical Name: 1-Isothiocyanato-PEG3-azide
  • CAS Number: 1310686-23-7
  • Molecular Formula: C9H16N4O3S
  • Molecular Weight: 260.31
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 06:41:58
  • Modify Date: 2024-01-17 06:03:26
  • 1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-Isothiocyanato-PEG3-azide
Description 1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C9H16N4O3S
Molecular Weight 260.31