Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: 2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2086689-02-1

2086689-02-1 structure

2086689-02-1 structure

Name: 2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane
Chemical Name: 2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
CAS Number: 2086689-02-1
Molecular Formula: C₁₉H₃₁N₃O₈S
Molecular Weight: 461.53
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:37:41
Modify Date: 2024-01-02 13:12:16
2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
Synonyms	MFCD30723274

Description	2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₉H₃₁N₃O₈S
Molecular Weight	461.53