653600-56-7

653600-56-7 structure

Name: 1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos
Chemical Name: Ac4GalNAz
CAS Number: 653600-56-7
Molecular Formula: C₁₆H₂₂N₄O₁₀
Molecular Weight: 430.37
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 16:48:32
Modify Date: 2024-01-02 10:40:07
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Ac4GalNAz

Description	Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.