2100306-48-5

2100306-48-5 structure
2100306-48-5 structure
  • Name: Ald-PEG1-t-butyl ester
  • Chemical Name: Ald-PEG1-C2-Boc
  • CAS Number: 2100306-48-5
  • Molecular Formula: C10H18O4
  • Molecular Weight: 202.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:19:15
  • Modify Date: 2024-02-03 23:17:13
  • Ald-PEG1-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-PEG1-C2-Boc
Synonyms MFCD30723216
Description Ald-PEG1-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H18O4
Molecular Weight 202.25