2170987-96-7

2170987-96-7 structure

2170987-96-7 structure

Name: H2N-PEG24-CH2CH2COOtBu
Chemical Name: Amino-PEG24-Boc
CAS Number: 2170987-96-7
Molecular Formula: C₅₅H₁₁₁NO₂₆
Molecular Weight: 1202.46
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:13:48
Modify Date: 2024-01-15 18:15:01
Amino-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Amino-PEG24-Boc
Synonyms	MFCD11041158

Description	Amino-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₅H₁₁₁NO₂₆
Molecular Weight	1202.46