1492056-71-9

1492056-71-9 structure

Name: Amino-PEG4-Val-Cit-PAB-MMAE
Chemical Name: Amino-PEG4-Val-Cit-PAB-MMAE
CAS Number: 1492056-71-9
Molecular Formula: C₆₉H₁₁₅N₁₁O₁₇
Molecular Weight: 1370.71
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-06-01 16:24:13
Modify Date: 2024-01-02 19:46:17
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Amino-PEG4-Val-Cit-PAB-MMAE

Description	Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.