2100306-82-7

2100306-82-7 structure
2100306-82-7 structure
  • Name: Aminooxy-PEG4-t-butyl ester
  • Chemical Name: Aminooxy-PEG4-C2-Boc
  • CAS Number: 2100306-82-7
  • Molecular Formula: C15H31NO7
  • Molecular Weight: 337.41
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:13:36
  • Modify Date: 2024-01-16 19:55:29
  • Aminooxy-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Aminooxy-PEG4-C2-Boc
Synonyms MFCD30730368
Description Aminooxy-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H31NO7
Molecular Weight 337.41