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2062663-62-9

2062663-62-9 structure
2062663-62-9 structure
  • Name: Aminooxy-PEG4-CH2CO2tBu
  • Chemical Name: Aminooxy-PEG4-CH2-Boc
  • CAS Number: 2062663-62-9
  • Molecular Formula: C14H29NO7
  • Molecular Weight: 323.38
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 01:45:35
  • Modify Date: 2024-01-09 15:35:35
  • Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Aminooxy-PEG4-CH2-Boc
Synonyms MFCD30536168
Description Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H29NO7
Molecular Weight 323.38