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1835759-88-0

1835759-88-0 structure
1835759-88-0 structure
  • Name: Azido-PEG1-methylamine
  • Chemical Name: Azido-PEG1-C2-methylamine
  • CAS Number: 1835759-88-0
  • Molecular Formula: C5H12N4O
  • Molecular Weight: 144.17
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 00:01:16
  • Modify Date: 2024-01-23 11:40:57
  • Azido-PEG1-C2-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG1-C2-methylamine
Description Azido-PEG1-C2-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C5H12N4O
Molecular Weight 144.17