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1835759-80-2

1835759-80-2 structure
1835759-80-2 structure
  • Name: Azido-PEG1-methyl ester
  • Chemical Name: Azido-PEG1-methyl ester
  • CAS Number: 1835759-80-2
  • Molecular Formula: C6H11N3O3
  • Molecular Weight: 173.17
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:37:51
  • Modify Date: 2024-01-07 06:43:04
  • Azido-PEG1-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG1-methyl ester
Description Azido-PEG1-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H11N3O3
Molecular Weight 173.17