2055023-76-0

2055023-76-0 structure

2055023-76-0 structure

Name: Azido-PEG3-Sulfone-PEG4-Boc
Chemical Name: Azido-PEG3-Sulfone-PEG4-Boc
CAS Number: 2055023-76-0
Molecular Formula: C₂₃H₄₅N₃O₁₁S
Molecular Weight: 571.68
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:27:57
Modify Date: 2024-01-10 16:20:22
Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG3-Sulfone-PEG4-Boc

Description	Azido-PEG3-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₄₅N₃O₁₁S
Molecular Weight	571.68