1421933-29-0

1421933-29-0 structure

Name: Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Chemical Name: Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
CAS Number: 1421933-29-0
Molecular Formula: C₃₆H₆₆N₄O₁₄
Molecular Weight: 778.93
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 09:10:04
Modify Date: 2024-01-09 17:44:04
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane

Description	Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₆H₆₆N₄O₁₄
Molecular Weight	778.93