2408505-11-1

2408505-11-1 structure

2408505-11-1 structure

Name: Biotin-PEG2-C1-aldehyde
Chemical Name: Biotin-PEG2-C1-aldehyde
CAS Number: 2408505-11-1
Molecular Formula: C₁₆H₂₇N₃O₅S
Molecular Weight: 373.47
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:03:38
Modify Date: 2024-01-17 00:29:42
Biotin-PEG2-C1-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG2-C1-aldehyde

Description	Biotin-PEG2-C1-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₆H₂₇N₃O₅S
Molecular Weight	373.47