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189209-28-7

189209-28-7 structure
189209-28-7 structure
  • Name: Biotin-PEG5-NH-Boc
  • Chemical Name: Biotin-PEG5-NH-Boc
  • CAS Number: 189209-28-7
  • Molecular Formula: C27H50N4O9S
  • Molecular Weight: 606.77
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:21:11
  • Modify Date: 2024-01-09 19:57:00
  • Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG5-NH-Boc
Synonyms MFCD30527395
Description Biotin-PEG5-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C27H50N4O9S
Molecular Weight 606.77