2144775-48-2

2144775-48-2 structure

2144775-48-2 structure

Name: Biotin-PEG6-Thalidomide
Chemical Name: Biotin-PEG6-Thalidomide
CAS Number: 2144775-48-2
Molecular Formula: C₃₇H₅₃N₅O₁₂S
Molecular Weight: 791.91
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:40:14
Modify Date: 2024-01-08 15:36:08
Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG6-Thalidomide
Synonyms	MFCD31561114

Description	Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₇H₅₃N₅O₁₂S
Molecular Weight	791.91