2353409-77-3

2353409-77-3 structure
2353409-77-3 structure
  • Name: Bis-(m-PEG8-amido)-hexanoic acid
  • Chemical Name: Bis-(m-PEG8-amido)-hexanoic acid
  • CAS Number: 2353409-77-3
  • Molecular Formula: C42H82N2O22
  • Molecular Weight: 967.10
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:22:12
  • Modify Date: 2024-01-08 11:00:50
  • Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-(m-PEG8-amido)-hexanoic acid
Description Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C42H82N2O22
Molecular Weight 967.10