1426164-52-4

1426164-52-4 structure
1426164-52-4 structure
  • Name: Bis-Mal-Lysine-PEG4-acid
  • Chemical Name: Bis-Mal-Lysine-PEG4-acid
  • CAS Number: 1426164-52-4
  • Molecular Formula: C31H45N5O13
  • Molecular Weight: 695.71
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:07:17
  • Modify Date: 2024-04-09 12:44:49
  • Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-Mal-Lysine-PEG4-acid
Synonyms MFCD28385462
Description Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C31H45N5O13
Molecular Weight 695.71