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252378-69-1

252378-69-1 structure
252378-69-1 structure
  • Name: t-Boc-Aminooxy-PEG2-amine
  • Chemical Name: Boc-Aminooxy-PEG2-C2-amine
  • CAS Number: 252378-69-1
  • Molecular Formula: C11H24N2O5
  • Molecular Weight: 264.32
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:01:50
  • Modify Date: 2024-01-09 19:37:07
  • Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Aminooxy-PEG2-C2-amine
Synonyms MFCD29079399
Description Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H24N2O5
Molecular Weight 264.32