1447797-72-9

1447797-72-9 structure

1447797-72-9 structure

Name: T-Boc-n-amido-peg4-ms
Chemical Name: Boc-NH-PEG4-Ms
CAS Number: 1447797-72-9
Molecular Formula: C₁₄H₂₉NO₈S
Molecular Weight: 371.45
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 13:05:12
Modify Date: 2024-01-10 07:46:08
Boc-NH-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-NH-PEG4-Ms
Synonyms	MFCD30182028

Description	Boc-NH-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₄H₂₉NO₈S
Molecular Weight	371.45