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1262991-52-5

1262991-52-5 structure
1262991-52-5 structure
  • Name: t-Boc-N-Amido-PEG6-propargyl
  • Chemical Name: Boc-NH-PEG6-propargyl
  • CAS Number: 1262991-52-5
  • Molecular Formula: C20H37NO8
  • Molecular Weight: 419.51
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:26:19
  • Modify Date: 2024-01-08 12:08:46
  • Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG6-propargyl
Synonyms MFCD30536151
Description Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C20H37NO8
Molecular Weight 419.51