2112731-50-5

2112731-50-5 structure
2112731-50-5 structure
  • Name: t-boc-N-amido-PEG9-azide
  • Chemical Name: Boc-NH-PEG9-azide
  • CAS Number: 2112731-50-5
  • Molecular Formula: C25H50N4O11
  • Molecular Weight: 582.68
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:45:45
  • Modify Date: 2024-01-09 21:44:33
  • Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG9-azide
Description Boc-NH-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H50N4O11
Molecular Weight 582.68