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1817735-45-7

1817735-45-7 structure
1817735-45-7 structure
  • Name: Carboxy-PEG2-sulfonic acid
  • Chemical Name: Carboxy-PEG2-sulfonic acid
  • CAS Number: 1817735-45-7
  • Molecular Formula: C7H14O7S
  • Molecular Weight: 242.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:10:23
  • Modify Date: 2024-01-12 12:07:57
  • Carboxy-PEG2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Carboxy-PEG2-sulfonic acid
Synonyms MFCD29042371
Description Carboxy-PEG2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C7H14O7S
Molecular Weight 242.25