2353410-09-8

2353410-09-8 structure

2353410-09-8 structure

Name: Cbz-aminooxy-PEG8-acid
Chemical Name: Cbz-aminooxy-PEG8-acid
CAS Number: 2353410-09-8
Molecular Formula: C₂₇H₄₅NO₁₃
Molecular Weight: 591.65
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:56:13
Modify Date: 2024-01-03 12:05:11
Cbz-aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Cbz-aminooxy-PEG8-acid

Description	Cbz-aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₄₅NO₁₃
Molecular Weight	591.65