2377004-08-3

2377004-08-3 structure
2377004-08-3 structure
  • Name: DBCO-PEG2-NH-Boc
  • Chemical Name: DBCO-PEG2-NH-Boc
  • CAS Number: 2377004-08-3
  • Molecular Formula: C30H37N3O6
  • Molecular Weight: 535.63
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:53:28
  • Modify Date: 2024-01-11 12:17:46
  • DBCO-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-PEG2-NH-Boc
Synonyms MFCD32207037
Description DBCO-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C30H37N3O6
Molecular Weight 535.63