2112738-14-2

2112738-14-2 structure
2112738-14-2 structure
  • Name: DSPE-PEG4-DBCO
  • Chemical Name: DSPE-PEG4-DBCO
  • CAS Number: 2112738-14-2
  • Molecular Formula: C71H116N3O15P
  • Molecular Weight: 1282.67
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:57:30
  • Modify Date: 2024-02-28 03:12:35
  • DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DSPE-PEG4-DBCO
Synonyms MFCD30828684
Description DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C71H116N3O15P
Molecular Weight 1282.67