2112738-14-2

2112738-14-2 structure

2112738-14-2 structure

Name: DSPE-PEG4-DBCO
Chemical Name: DSPE-PEG4-DBCO
CAS Number: 2112738-14-2
Molecular Formula: C₇₁H₁₁₆N₃O₁₅P
Molecular Weight: 1282.67
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 16:57:30
Modify Date: 2024-02-28 03:12:35
DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DSPE-PEG4-DBCO
Synonyms	MFCD30828684

Description	DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₇₁H₁₁₆N₃O₁₅P
Molecular Weight	1282.67