2141976-33-0

2141976-33-0 structure

Name: endo-Bicyclo[6.1.0]non-4-yn-9-ylmethyl (15-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-13-oxo-3,6,9-trioxa-12-azapentadecyl)carbamate
Chemical Name: endo-BCN-PEG3-mal
CAS Number: 2141976-33-0
Molecular Formula: C₂₆H₃₇N₃O₈
Molecular Weight: 519.59
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 08:49:24
Modify Date: 2024-07-17 20:02:37
endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	endo-BCN-PEG3-mal
Synonyms	MFCD31811466

Description	endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₆H₃₇N₃O₈
Molecular Weight	519.59