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2055105-59-2

2055105-59-2 structure
2055105-59-2 structure
  • Name: Fluorescein-PEG6-bis-NHS ester
  • Chemical Name: Fluorescein-PEG6-bis-NHS ester
  • CAS Number: 2055105-59-2
  • Molecular Formula: C44H50N4O17S
  • Molecular Weight: 938.95
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 00:12:56
  • Modify Date: 2024-01-11 05:05:53
  • Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fluorescein-PEG6-bis-NHS ester
Synonyms MFCD30527407
Description Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C44H50N4O17S
Molecular Weight 938.95