2170484-59-8

2170484-59-8 structure

Name: 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid
Chemical Name: Fmoc-N-PEG24-acid
CAS Number: 2170484-59-8
Molecular Formula: C₆₆H₁₁₃NO₂₈
Molecular Weight: 1368.59
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:47:24
Modify Date: 2024-01-09 12:06:04
Fmoc-N-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fmoc-N-PEG24-acid
Synonyms	MFCD11041159

Description	Fmoc-N-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₆₆H₁₁₃NO₂₈
Molecular Weight	1368.59