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2128735-25-9

2128735-25-9 structure
2128735-25-9 structure
  • Name: Fmoc-PEG3-CH2CO2-NHS
  • Chemical Name: Fmoc-N-PEG3-CH2-NHS ester
  • CAS Number: 2128735-25-9
  • Molecular Formula: C27H30N2O9
  • Molecular Weight: 526.54
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:05:09
  • Modify Date: 2024-01-11 22:56:43
  • Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name Fmoc-N-PEG3-CH2-NHS ester
Synonyms MFCD31536755
Description Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Molecular Formula C27H30N2O9
Molecular Weight 526.54

Chemsrc provides CAS#:2128735-25-9 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2128735-25-9 | Chemsrc address: https://m.chemsrc.com/en/baike/1565341.html

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