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2170240-98-7

2170240-98-7 structure
2170240-98-7 structure
  • Name: Fmoc-NMe-PEG4-acid
  • Chemical Name: Fmoc-NMe-PEG4-C2-acid
  • CAS Number: 2170240-98-7
  • Molecular Formula: C27H35NO8
  • Molecular Weight: 501.57
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:47:39
  • Modify Date: 2024-01-19 23:29:17
  • Fmoc-NMe-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-NMe-PEG4-C2-acid
Synonyms MFCD29090721
Description Fmoc-NMe-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C27H35NO8
Molecular Weight 501.57