2354291-37-3

2354291-37-3 structure

2354291-37-3 structure

Name: Gly-PEG3-endo-BCN
Chemical Name: Gly-PEG3-endo-BCN
CAS Number: 2354291-37-3
Molecular Formula: C₂₃H₃₉N₃O₆
Molecular Weight: 453.57
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:26:03
Modify Date: 2024-01-09 11:26:53
Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Gly-PEG3-endo-BCN

Description	Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₃₉N₃O₆
Molecular Weight	453.57