Shanghai Nianxing Industrial Co., Ltd
China
Product Name: HO-PEG10-CH2COOH
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2250056-53-0

2250056-53-0 structure

2250056-53-0 structure

Name: 32-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-oic acid
Chemical Name: HO-PEG10-CH2COOH
CAS Number: 2250056-53-0
Molecular Formula: C₂₂H₄₄O₁₃
Molecular Weight: 516.58
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:29:14
Modify Date: 2024-02-24 19:48:02
HO-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HO-PEG10-CH2COOH

Description	HO-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₂H₄₄O₁₃
Molecular Weight	516.58