780006-30-6

780006-30-6 structure
780006-30-6 structure
  • Name: HO-PEG8-CH2COOH
  • Chemical Name: HO-PEG8-CH2COOH
  • CAS Number: 780006-30-6
  • Molecular Formula: C18H36O11
  • Molecular Weight: 428.47
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:14:13
  • Modify Date: 2024-01-09 13:02:31
  • HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name HO-PEG8-CH2COOH
Description HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C18H36O11
Molecular Weight 428.47