2100306-77-0

2100306-77-0 structure
2100306-77-0 structure
  • Name: Hydroxy-Amino-bis(PEG2-propargyl)
  • Chemical Name: Hydroxy-Amino-bis(PEG2-propargyl)
  • CAS Number: 2100306-77-0
  • Molecular Formula: C16H27NO5
  • Molecular Weight: 313.39
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:02:48
  • Modify Date: 2024-01-10 22:14:19
  • Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-Amino-bis(PEG2-propargyl)
Synonyms MFCD30723249
Description Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H27NO5
Molecular Weight 313.39