2378049-28-4

2378049-28-4 structure
2378049-28-4 structure
  • Name: Hydroxy-PEG7-CH2-Boc
  • Chemical Name: Hydroxy-PEG7-CH2-Boc
  • CAS Number: 2378049-28-4
  • Molecular Formula: C20H40O10
  • Molecular Weight: 440.53
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:49:51
  • Modify Date: 2024-01-10 11:20:00
  • Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-PEG7-CH2-Boc
Description Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C20H40O10
Molecular Weight 440.53