2407442-47-9

2407442-47-9 structure

Name: Lipoamido-PEG12-carboxylic Acid
Chemical Name: Lipoamido-PEG12-acid
CAS Number: 2407442-47-9
Molecular Formula: C₃₅H₆₇NO₁₅S₂
Molecular Weight: 806.03
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:04:10
Modify Date: 2024-01-09 20:24:26
Lipoamido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Lipoamido-PEG12-acid

Description	Lipoamido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562