Shanghai Nianxing Industrial Co., Ltd
China
Product Name: m-PEG12-COO-propanoic acid
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Purity: 95.0%
Stocking Period: 10 Day
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2168540-50-7

2168540-50-7 structure

2168540-50-7 structure

Name: m-PEG12-COO-propanoic acid
Chemical Name: m-PEG12-COO-propanoic acid
CAS Number: 2168540-50-7
Molecular Formula: C₂₉H₅₆O₁₆
Molecular Weight: 660.75
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 05:40:02
Modify Date: 2024-01-10 10:19:57
m-PEG12-COO-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG12-COO-propanoic acid

Description	m-PEG12-COO-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₅₆O₁₆
Molecular Weight	660.75

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