60696-83-5

60696-83-5 structure

Name: m-PEG3-Ms
Chemical Name: m-PEG2-Ms
CAS Number: 60696-83-5
Molecular Formula: C₆H₁₄O₅S
Molecular Weight: 198.24
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:02:46
Modify Date: 2024-01-14 16:01:12
m-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG2-Ms
Synonyms	MFCD00955893

Description	m-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562