1919045-04-7

1919045-04-7 structure
1919045-04-7 structure
  • Name: m-PEG3-Sulfone-PEG3-acid
  • Chemical Name: m-PEG3-Sulfone-PEG3-acid
  • CAS Number: 1919045-04-7
  • Molecular Formula: C16H32O10S
  • Molecular Weight: 416.48
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:45:40
  • Modify Date: 2024-01-05 17:54:36
  • m-PEG3-Sulfone-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG3-Sulfone-PEG3-acid
Synonyms MFCD29918255
Description m-PEG3-Sulfone-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H32O10S
Molecular Weight 416.48