1895922-76-5

1895922-76-5 structure

1895922-76-5 structure

Name: m-PEG3-Sulfone-PEG3-azide
Chemical Name: m-PEG3-Sulfone-PEG3-azide
CAS Number: 1895922-76-5
Molecular Formula: C₁₅H₃₁N₃O₈S
Molecular Weight: 413.49
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 15:54:29
Modify Date: 2024-01-05 18:33:41
m-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG3-Sulfone-PEG3-azide

Description	m-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₅H₃₁N₃O₈S
Molecular Weight	413.49