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2028281-85-6

2028281-85-6 structure
2028281-85-6 structure
  • Name: m-PEG4-(CH2)8-phosphonic acid
  • Chemical Name: m-PEG4-(CH2)6-Phosphonic acid
  • CAS Number: 2028281-85-6
  • Molecular Formula: C15H33O7P
  • Molecular Weight: 356.39
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:18:39
  • Modify Date: 2024-01-09 10:19:52
  • m-PEG4-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG4-(CH2)6-Phosphonic acid
Description m-PEG4-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H33O7P
Molecular Weight 356.39