1872433-62-9

1872433-62-9 structure

1872433-62-9 structure

Name: m-PEG4-phosphonic acid
Chemical Name: m-PEG4-phosphonic acid
CAS Number: 1872433-62-9
Molecular Formula: C₉H₂₁O₇P
Molecular Weight: 272.23
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:16:17
Modify Date: 2024-01-12 12:47:54
m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG4-phosphonic acid
Synonyms	MFCD29079386

Description	m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₉H₂₁O₇P
Molecular Weight	272.23