1449390-64-0

1449390-64-0 structure
1449390-64-0 structure
  • Name: m-PEG6-Hydrazide
  • Chemical Name: m-PEG6-Hydrazide
  • CAS Number: 1449390-64-0
  • Molecular Formula: C14H30N2O7
  • Molecular Weight: 338.40
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 07:18:46
  • Modify Date: 2024-01-10 13:11:15
  • m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG6-Hydrazide
Description m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C14H30N2O7
Molecular Weight 338.40