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678150-56-6

678150-56-6 structure
678150-56-6 structure
  • Name: m-PEG7-4-nitrophenyl carbonate
  • Chemical Name: m-PEG7-4-nitrophenyl carbonate
  • CAS Number: 678150-56-6
  • Molecular Formula: C20H31NO11
  • Molecular Weight: 461.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:42:29
  • Modify Date: 2024-01-10 00:01:44
  • m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG7-4-nitrophenyl carbonate
Description m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C20H31NO11
Molecular Weight 461.46