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1056881-04-9

1056881-04-9 structure
1056881-04-9 structure
  • Name: m-PEG8-bromide
  • Chemical Name: m-PEG8-Br
  • CAS Number: 1056881-04-9
  • Molecular Formula: C17H35BrO8
  • Molecular Weight: 447.36
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:42:06
  • Modify Date: 2025-08-25 03:50:26
  • m-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG8-Br
Synonyms MFCD31380391
Description m-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.198±0.06 g/cm3(Predicted)
Boiling Point 462.5±40.0 °C(Predicted)
Molecular Formula C17H35BrO8
Molecular Weight 447.36
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